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microarray suite (mas) v5.0 software  (Thermo Fisher)


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    Thermo Fisher microarray suite (mas) v5.0 software
    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA <t>microarray.</t> A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
    Microarray Suite (Mas) V5.0 Software, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray suite (mas) v5.0 software/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    microarray suite (mas) v5.0 software - by Bioz Stars, 2026-04
    90/100 stars

    Images

    1) Product Images from "The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell cycle progression in malignant bladder cancer cells in vitro and in vivo"

    Article Title: The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell cycle progression in malignant bladder cancer cells in vitro and in vivo

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    doi: 10.1158/1078-0432.CCR-12-2383

    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA microarray. A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
    Figure Legend Snippet: Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA microarray. A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.

    Techniques Used: Microarray, Real-time Polymerase Chain Reaction, Expressing



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    microarray suite (mas) v5.0 software  (Thermo Fisher)
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    Thermo Fisher microarray suite (mas) v5.0 software
    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA <t>microarray.</t> A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
    Microarray Suite (Mas) V5.0 Software, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray suite (mas) v5.0 software/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    microarray suite (mas) v5.0 software - by Bioz Stars, 2026-04
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    microarray analysis suite (mas v5.0  (Thermo Fisher)
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    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA <t>microarray.</t> A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
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    mas 5.0 (microarray suite v5.0  (Thermo Fisher)
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    Thermo Fisher mas 5.0 (microarray suite v5.0
    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA <t>microarray.</t> A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
    Mas 5.0 (Microarray Suite V5.0, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mas 5.0 (microarray suite v5.0/product/Thermo Fisher
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    microarray suite software (mas v5.0  (Thermo Fisher)
    90
    Thermo Fisher microarray suite software (mas v5.0
    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA <t>microarray.</t> A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.
    Microarray Suite Software (Mas V5.0, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/microarray suite software (mas v5.0/product/Thermo Fisher
    Average 90 stars, based on 1 article reviews
    microarray suite software (mas v5.0 - by Bioz Stars, 2026-04
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA microarray. A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.

    Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

    Article Title: The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell cycle progression in malignant bladder cancer cells in vitro and in vivo

    doi: 10.1158/1078-0432.CCR-12-2383

    Figure Lengend Snippet: Mitotic spindle checkpoint genes are broadly overexpressed in human urothelial carcinoma. A, Human samples of normal urothelium (N=10) and urothelial carcinoma of the bladder (N=8) were subjected to RNA microarray. A subset of 13 gene transcripts related to the mitotic spindle checkpoint, including Aurora A and B, were upregulated at least 5-fold in the urothelial carcinoma compared to the normal urothelium. B, Upregulation of these genes was validated by two-step quantitative real-time PCR on a separate set of human samples of urothelial carcinoma (N=3) and normal urothelium (N=3). 10 of 13 genes (asterisked) demonstrated statistical significance (T-test P-value < 0.05) for differential expression in urothelial carcinoma compared to normal urothelium.

    Article Snippet: Expression values were generated by using Microarray Suite (MAS) v5.0 software (Affymetrix).

    Techniques: Microarray, Real-time Polymerase Chain Reaction, Expressing